Washington: Researchers at the University of Cincinnati have tested a new combination therapy in animal models to see if they could find a way to make an already effective treatment even better. Since they`re using a Food and Drug Administration-approved drug to do it, this could help humans sooner than later.
These findings are published in the journal Cancer Letters. Christina Wicker, PhD, a postdoctoral fellow in the lab of Vinita Takiar, MD, PhD, led this research which she says will hopefully extend the lives of patients one day.”Head and neck cancer, like any cancer, is truly life-altering,” she says.
“Head and neck cancer could impact your throat, tongue or nose, and patients often can`t swallow, talk or eat; it truly takes away some of the most social, enjoyable parts of life.”
Researchers in this study combined radiation therapy with a drug (telaglenastat) that stops a key enzyme in a cell pathway that becomes altered in cancer cells, causing those cells to grow rapidly and resist treatment. Wicker says this drug has already been studied in multiple clinical trials to see if it could improve treatment of various cancers.
“Until now, no one has examined if this drug has…